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KMID : 1041220000420020093
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Journal of Sericultural and Entomological Science
2000 Volume.42 No. 2 p.93 ~ p.98
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Effect of Silkworm Powder on Oxygen radicals and Their Scavenger Enzymes in Brain membranes of SD Rats
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Abstract
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This study was designed to inbestigate effect of selkworm poweder on oxygen radicals and their scavenger enzymes in brain membranes of SD rats. Hydroxyl radical (OH) levels resulted in a considerable decreases in brain mitochondria fraction. Superoxide radical (O_2) levels were a slightly decreased in brain cytosol fraction. Lipid peroxide (LPO) and Oxidized protein (OP) levels were significantly decreased in brain mitochondria fraction. Cu and Zn-SOD activities were effectively increased in brain cytosol fraction. GSHPx activity was considerably increased in brain cytosol fraction. These results suggest that anti-aging effect of silkworm plays an effective role in attenuating an oxidative stress and increasing a scravenger enzymeactivity in brain membranes.
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